Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21697612 | 0.85 | SMN1; SMN2 (0.37) | F9F10RAB9ASMN1; SMN2DRD1 | |
| SCHEMBL16020910 | 0.85 | PTGES (0.35) | RAB9APTGESALOX5PSEN1S1PR1 | |
| SCHEMBL20741824 | 0.84 | ABCB1 (0.41) | RAB9ASMN1; SMN2DRD1SLC6A2SLC6A4 | |
| SCHEMBL21697645 | 0.82 | HTR2A (0.37) | MRGPRX4F9F10RAB9ASMN1; SMN2 | |
| SCHEMBL16018672 | 0.78 | ALOX5 (0.36) | PTGESALOX5 | |
| SCHEMBL21697564 | 0.77 | FFAR1 (0.37) | MRGPRX4F9F10RAB9ASMN1; SMN2 | |
| SCHEMBL21697652 | 0.77 | THRB (0.38) | SMN1; SMN2DRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21697575 | 0.76 | THRB (0.38) | SMN1; SMN2 | |
| SCHEMBL21697589 | 0.75 | PTGER1 (0.37) | MRGPRX4RAB9ASMN1; SMN2PTGER1 | |
| SCHEMBL16020940 | 0.72 | RAB9A (0.34) | RAB9APTGESALOX5SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968258-B1 | DUAL SGLT1/SGLT2 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-02-12 | — | — | EP | disclosed |