Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 7/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 5/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GJB2 | P29033 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21697613 | 0.92 | SSTR1 (0.36) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL21697623 | 0.90 | SLC5A2 (0.37) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL21697600 | 0.90 | SLC5A2 (0.41) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL21697642 | 0.90 | SSTR1 (0.37) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL21697577 | 0.85 | SSTR1 (0.34) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL21697647 | 0.85 | SSTR1 (0.36) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL20741834 | 0.85 | SLC5A2 (0.42) | SLC5A2SLC5A1SSTR4 | |
| SCHEMBL21697562 | 0.84 | SSTR1 (0.33) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL21697591 | 0.84 | PTGER1 (0.33) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL16018673 | 0.84 | SLC5A2 (0.41) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968258-B1 | DUAL SGLT1/SGLT2 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-02-12 | — | — | EP | disclosed |