Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 11/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 8/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21697613 | 0.91 | SSTR1 (0.36) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL21697623 | 0.91 | SLC5A2 (0.37) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL21697642 | 0.91 | SSTR1 (0.37) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL21697646 | 0.90 | SLC5A2 (0.40) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL21697591 | 0.86 | PTGER1 (0.33) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL21697647 | 0.84 | SSTR1 (0.36) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL21697562 | 0.83 | SSTR1 (0.33) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL21697655 | 0.82 | SSTR1 (0.37) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL16656269 | 0.82 | SLC5A2 (0.40) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 | |
| SCHEMBL16018609 | 0.82 | SLC5A2 (0.40) | SLC5A2SLC5A1SSTR1SSTR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968258-B1 | DUAL SGLT1/SGLT2 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-02-12 | — | — | EP | disclosed |