Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18131814 | 0.87 | PTGS1 (0.56) | ALDH1A1GAAHTTSMN1; SMN2PTGS1 | |
| SCHEMBL24242314 | 0.83 | KDM4E (0.41) | ALDH1A1GAAHTTSMN1; SMN2PTGS1 | |
| SCHEMBL18131802 | 0.83 | PTGS1 (0.61) | ALDH1A1GAAHTTSMN1; SMN2PTGS1 | |
| SCHEMBL20100079 | 0.80 | ALDH1A1 (0.67) | ALDH1A1GAAHTTSMN1; SMN2PTGS1 | |
| SCHEMBL24611917 | 0.78 | PTGS1 (0.68) | ALDH1A1GAAHTTSMN1; SMN2PTGS1 | |
| SCHEMBL20229616 | 0.76 | ALDH1A1 (0.51) | ALDH1A1GAAHTTSMN1; SMN2PTGS1 | |
| SCHEMBL18131817 | 0.76 | MAPK1 (0.44) | ALDH1A1GAAHTTSMN1; SMN2PTGS1 | |
| SCHEMBL22519128 | 0.75 | KDM4E (0.46) | ALDH1A1GAAHTTSMN1; SMN2PTGS1 | |
| SCHEMBL20100107 | 0.75 | KDM4E (0.52) | ALDH1A1GAAHTTSMN1; SMN2KDM4E | |
| SCHEMBL19798102 | 0.73 | ALDH1A1 (0.48) | ALDH1A1GAASMN1; SMN2PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3280716-B1 | IMIDAZO[1,2-A]PYRIDIN-2-YL DERIVATIVES AS PESTICIDES AND INTERMEDIATES THEREOF | BAYER CROPSCIENCE AG (DE) | 2020-02-12 | — | — | EP | disclosed |