Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19432683 | 0.81 | — | — | |
| SCHEMBL23560299 | 0.79 | EPHX2 (0.34) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21064326 | 0.79 | — | — | |
| SCHEMBL10465603 | 0.76 | NPC1 (0.36) | KMT2AMMP1MMP2MMP3MMP9 | |
| SCHEMBL20629281 | 0.75 | — | — | |
| SCHEMBL24095015 | 0.75 | CNR1 (0.33) | CNR1MMP1MMP2MMP3MMP9 | |
| SCHEMBL24689474 | 0.74 | KMT2A (0.32) | KMT2A | |
| SCHEMBL24377548 | 0.74 | CNR2 (0.32) | CNR1 | |
| SCHEMBL22180358 | 0.74 | MMP1 (0.38) | CNR1KMT2AMMP1MMP2MMP3 | |
| SCHEMBL21190234 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166603-B1 | TREATMENT OF LEUKEMIA WITH HISTONE DEACETYLASE INHIBITORS | ACETYLON PHARMACEUTICALS INC (US) | 2020-02-12 | — | — | EP | disclosed |