SCHEMBL21699360

SCHEMBL21699360

Brc1ccc2c(c1)c1c3ccccc3n(-c3ccccc3)c1n2-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ATM Q13315 1/20 0.48
ALDH1A1 P00352 2/20 0.40
RXFP1 Q9HBX9 1/20 0.40
TSPO P30536 2/20 0.39
LIG1 P18858 1/20 0.36
KMT2A Q03164 2/20 0.36
JAK2 O60674 1/20 0.36
JAK3 P52333 1/20 0.36
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
BRCA1 P38398 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CA9 Q16790 1/20 0.35
MAPK8 P45983 2/20 0.35
IL1R1 P14778 1/20 0.35
MAPK1 P28482 1/20 0.34
PGR P06401 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21699336 0.90 L3MBTL1 (0.48) L3MBTL1KDM4EATMALDH1A1RXFP1
SCHEMBL21711022 0.89 L3MBTL1 (0.55) L3MBTL1KDM4EATMALDH1A1RXFP1
SCHEMBL21699145 0.88 L3MBTL1 (0.53) L3MBTL1KDM4EATMALDH1A1RXFP1
SCHEMBL15114261 0.87 KDM4E (0.48) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL26756274 0.87 L3MBTL1 (0.48) L3MBTL1KDM4EATMALDH1A1RXFP1
SCHEMBL21699369 0.85 L3MBTL1 (0.43) L3MBTL1KDM4EATMALDH1A1RXFP1
SCHEMBL16276631 0.85 L3MBTL1 (0.53) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL13562905 0.84 L3MBTL1 (0.67) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL16276611 0.83 L3MBTL1 (0.52) L3MBTL1KDM4EATMALDH1A1TSPO
SCHEMBL261514 0.83 L3MBTL1 (0.67) L3MBTL1KDM4EATMALDH1A1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608320-B1 ORGANIC ELECTROLUMINESCENCE DEVICE AND CONDENSED CYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2023-05-10 EP disclosed
US-20210104679-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2021-04-08 US disclosed
EP-3608320-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND CONDENSED CYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE Samsung Display Co., Ltd. (KR) 2020-02-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210104679-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SLCO4C1, OR10J3, SLCO2B1 L3MBTL1 265/4885KDM4E 1757/4885ATM 4671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.