Trifluoromethylbenzene

Trifluoromethylbenzene

SCHEMBL2169987

FC(F)(F)c1ccccc1.N

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.93
ALDH1A1 P00352 1/20 0.93
KIF11 P52732 4/20 0.65
TRPV6 Q9H1D0 2/20 0.52
CYP19A1 P11511 1/20 0.48
BACE1 P56817 1/20 0.46
PTPN1 P18031 1/20 0.46
MAPK1 P28482 1/20 0.46
KCNN4 O15554 1/20 0.45
RAB9A P51151 2/20 0.45
NPC1 O15118 1/20 0.45
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA5A P35218 1/20 0.44
CA9 Q16790 1/20 0.44
OPRM1 P35372 1/20 0.43
OPRL1 P41146 1/20 0.43
ACP3 P15309 1/20 0.43
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethylbenzene SCHEMBL8863222 1.00 TSHR (0.93) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL175647 0.97 TSHR (1.00) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL27760126 0.97 TSHR (1.00) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL8692 0.97 TSHR (1.00) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL14121438 0.93 TSHR (0.93) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL31609597 0.93 TSHR (0.93) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL1830622 0.93 TSHR (0.93) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL22806921 0.93 TSHR (0.93) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL7870246 0.93 TSHR (0.93) TSHRALDH1A1KIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL30957761 0.93 TSHR (0.93) TSHRALDH1A1KIF11TRPV6CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410555-B Preparation process of high-temperature-resistant special fluororubber 山东通泰橡胶股份有限公司 2024-06-04 CN claimed
CN-116410555-A Preparation process of high-temperature-resistant special fluororubber 山东通泰橡胶股份有限公司 2023-07-11 CN claimed
CN-109232434-A A kind of new method synthesizing flibanserin 湖北大学 2019-01-18 CN claimed
CN-108503551-A The solvent-free hydrogenation reduction process of mamino-trifluoromethyl benzene 江苏大华化学工业有限公司 2018-09-07 CN claimed
CN-106916052-A A kind of preparation method of m-trifluoromethyl phenol 内蒙古佳瑞米精细化工有限公司 2017-07-04 CN claimed
CN-106431936-A Method for processing fluoride ions in aminobenzotrifluoride 江苏丰华化学工业有限公司 2017-02-22 CN claimed
CN-106397109-A Synthetic method of trifluperidol medicine intermediate 3-bromobenzotrifluoride 厦门莱恩斯特信息科技有限公司 2017-02-15 CN claimed
CN-105439811-A Synthesis method of trifluperidol drug intermediate m-bromobenzotrifluoride CHENGDU ZHONGHENG HUATIE TECH CO LTD 2016-03-30 CN claimed
CN-104926734-A Preparation method of flibanserin Suzhou lixin pharmaceutical co ltd 2015-09-23 CN claimed
CN-102888609-A Stainless steel chemical polishing liquid NANJING DADI REFRIGERATION FOOD CO LTD 2013-01-23 CN claimed
CN-1763012-A Sodium niflumic acid production process GU YUMEI (CN) 2006-04-26 CN claimed
CN-116410555-B Preparation process of high-temperature-resistant special fluororubber 山东通泰橡胶股份有限公司 2024-06-04 CN disclosed
CN-107209146-B Electrochemical gas sensor and electrolyte for electrochemical gas sensor 德尔格安全股份两合公司 2024-03-12 CN disclosed
CN-116410555-A Preparation process of high-temperature-resistant special fluororubber 山东通泰橡胶股份有限公司 2023-07-11 CN disclosed
CN-110128500-A Prepare α-amide groups amide substance Ugi mixed solvent method 杭州迈世腾药物科技有限公司 2019-08-16 CN disclosed
CN-101875625-A Recrystallization method for improving trans-fluorochloridone content SUZHOU JIAHUI CHEMICAL CO LTD 2010-11-03 CN disclosed
CN-101003499-A Novel color former and recording material ASAHI CHEMICAL IND (JP) 2007-07-25 CN disclosed
CN-1303064-C Novel color-developing composition and recording material ASAHI CHEMICAL IND (JP) 2007-03-07 CN disclosed
CN-1763012-A Sodium niflumic acid production process GU YUMEI (CN) 2006-04-26 CN disclosed
CN-1496346-A Novel color-developing composition and recording material 旭化成株式会社 2004-05-12 CN disclosed