SCHEMBL2170167

SCHEMBL2170167

CCC(C)c1cc(Oc2c(Br)cc(C=NOc3ccccc3CC(=O)O)cc2Br)ccc1O

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRA P10827 17/20 0.51
THRB P10828 17/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2172343 0.83 MAPT (0.40) THRATHRB
SCHEMBL2171145 0.82 THRA (0.55) THRATHRB
SCHEMBL2171146 0.82 THRA (0.55) THRATHRB
SCHEMBL2172350 0.80 THRA (0.50) THRATHRB
SCHEMBL2172347 0.80 THRA (0.50) THRATHRB
SCHEMBL2170161 0.80 THRA (0.49) THRATHRB
SCHEMBL2182550 0.80 THRA (0.49) THRATHRB
SCHEMBL2172832 0.79 THRA (0.49) THRATHRB
SCHEMBL2172835 0.79 THRA (0.49) THRATHRB
SCHEMBL16496301 0.78 THRA (0.48) THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346814-A2 THYROID RECEPTOR LIGANDS Cadila Healthcare Limited (IN) 2011-07-27 EP claimed
WO-2010049946-A2 THYROID RECEPTOR LIGANDS CADILA HEALTHCARE LIMITED (IN) 2010-05-06 WO claimed