Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL867166 | 0.86 | CA1 (0.52) | CA1CA2CA12CA7CA9 | |
| Methylparaben SCHEMBL28757100 | 0.81 | CA1 (0.83) | CA1CA2CA12CA7CA9 | |
| Methylparaben SCHEMBL28550509 | 0.79 | CA1 (0.62) | CA1CA2CA12CA7CA9 | |
| SCHEMBL29110662 | 0.79 | TSHR (0.55) | CA1CA2HSD17B10TSHRALDH1A1 | |
| Phenylpropanol SCHEMBL25426604 | 0.79 | LMNA (0.83) | CA1CA2CA12CA9CA14 | |
| Methyl Benzoate SCHEMBL9685679 | 0.79 | TSHR (0.83) | CA1CA2CA12CA7CA9 | |
| Methylparaben SCHEMBL28210343 | 0.79 | CA1 (0.87) | CA1CA2CA12CA7CA9 | |
| Phenol SCHEMBL8167350 | 0.79 | CA1 (0.79) | CA1CA2CA12CA7CA9 | |
| Phenylpropanol SCHEMBL28602143 | 0.78 | LMNA (0.63) | LMNAHSD17B10ESR2KDM4EGAA | |
| Methylparaben SCHEMBL28558237 | 0.77 | CA1 (0.77) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346518-A1 | PROCESS FOR EXTRACTING CARDIAC GLYCOSIDES AND COMPOSITIONS | Nerium Biotechnology, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010045243-A1 | PROCESS FOR EXTRACTING CARDIAC GLYCODIDES AND COMPOSITIONS | NERIUM BIOTECHNOLOGY, INC. (US) | 2010-04-22 | — | — | WO | disclosed |