Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.55 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170206 | 1.00 | CNR2 (0.55) | CNR2MAP2K1SLC6A9CASP3CASP7 | |
| SCHEMBL3627815 | 0.86 | CNR2 (0.59) | CNR2MAP2K1 | |
| SCHEMBL1974220 | 0.86 | CNR2 (0.59) | CNR2MAP2K1 | |
| SCHEMBL1974225 | 0.86 | CNR2 (0.59) | CNR2MAP2K1 | |
| SCHEMBL2170926 | 0.83 | CNR2 (0.56) | CNR2 | |
| SCHEMBL2170919 | 0.83 | CNR2 (0.56) | CNR2 | |
| SCHEMBL2171056 | 0.80 | CNR2 (0.58) | CNR2 | |
| SCHEMBL2171041 | 0.80 | CNR2 (0.58) | CNR2 | |
| SCHEMBL2171809 | 0.79 | CHRM3 (0.51) | CNR2 | |
| SCHEMBL2170712 | 0.78 | CNR2 (0.51) | CNR2SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346843-A2 | SUBSTITUTED BENZAMIDES AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2011-07-27 | — | — | EP | claimed |
| WO-2010028338-A2 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-03-11 | — | — | WO | claimed |