Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 6/20 | 0.51 |
| ▸ | CNR2 | P34972 | 8/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1974220 | 0.90 | CNR2 (0.59) | CNR2IRAK4CHRNB1CHRNB2CHRNB4 | |
| SCHEMBL1974225 | 0.90 | CNR2 (0.59) | CNR2IRAK4CHRNB1CHRNB2CHRNB4 | |
| SCHEMBL3627815 | 0.90 | CNR2 (0.59) | CNR2IRAK4CHRNB1CHRNB2CHRNB4 | |
| SCHEMBL2170919 | 0.87 | CNR2 (0.56) | CNR2IRAK4CHRNB1CHRNB2CHRNB4 | |
| SCHEMBL2170926 | 0.87 | CNR2 (0.56) | CNR2IRAK4CHRNB1CHRNB2CHRNB4 | |
| SCHEMBL3227907 | 0.87 | CNR2 (0.50) | CHRM3CNR2HRH3 | |
| SCHEMBL3227903 | 0.87 | CNR2 (0.50) | CHRM3CNR2HRH3 | |
| SCHEMBL11457893 | 0.83 | CHRNB4 (0.54) | CHRM3CHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11466858 | 0.81 | CHRNB4 (0.52) | CHRM3CHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL29658346 | 0.81 | HTR6 (0.46) | CHRM3CNR2CHRNB1CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346843-A2 | SUBSTITUTED BENZAMIDES AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010028338-A2 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-03-11 | — | — | WO | disclosed |