Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23711629 | 1.00 | HPGD (0.50) | HPGDALDH1A1TP53SMN1; SMN2CTSL | |
| SCHEMBL23506229 | 1.00 | HPGD (0.50) | HPGDALDH1A1TP53SMN1; SMN2CTSL | |
| SCHEMBL21702241 | 0.95 | HPGD (0.48) | HPGDALDH1A1TP53SMN1; SMN2CTSL | |
| SCHEMBL23506334 | 0.95 | HPGD (0.48) | HPGDALDH1A1TP53SMN1; SMN2CTSL | |
| SCHEMBL23711763 | 0.89 | HDAC2 (0.41) | HPGDALDH1A1TP53SMN1; SMN2RAB9A | |
| SCHEMBL23711720 | 0.89 | TDP1 (0.45) | HPGDALDH1A1TP53SMN1; SMN2RAB9A | |
| SCHEMBL21702239 | 0.89 | RXFP1 (0.42) | HPGDALDH1A1TP53SMN1; SMN2CTSL | |
| SCHEMBL23506238 | 0.89 | RXFP1 (0.42) | HPGDALDH1A1TP53SMN1; SMN2CTSL | |
| SCHEMBL23506398 | 0.88 | CTSL (0.47) | HPGDALDH1A1TP53SMN1; SMN2CTSL | |
| SCHEMBL21702266 | 0.88 | CTSL (0.47) | HPGDALDH1A1TP53SMN1; SMN2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020030143-A1 | KETOAMIDE COMPOUND AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 中国科学院上海药物研究所 | 2020-02-13 | — | — | WO | disclosed |