Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ATP4A | P20648 | 1/20 | 0.30 |
| ▸ | ATP4B | P51164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25941085 | 0.87 | MAP4K1 (0.38) | MAP4K1 | |
| SCHEMBL21685669 | 0.86 | ALDH1A1 (0.46) | MAP4K1ELANE | |
| SCHEMBL21685237 | 0.75 | MAP4K1 (0.32) | MAP4K1ELANE | |
| SCHEMBL21685451 | 0.75 | DRD4 (0.40) | MAP4K1ATP4AATP4B | |
| SCHEMBL25941029 | 0.74 | MAP4K1 (0.52) | MAP4K1 | |
| SCHEMBL21685171 | 0.73 | MAP4K1 (0.54) | MAP4K1ELANE | |
| SCHEMBL21703236 | 0.72 | ELANE (0.33) | ELANE | |
| SCHEMBL31450500 | 0.70 | MAP4K1 (0.55) | MAP4K1 | |
| SCHEMBL31450727 | 0.70 | MAP4K1 (0.52) | MAP4K1 | |
| SCHEMBL21703024 | 0.70 | MAP4K1 (0.37) | MAP4K1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033784-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | SITARI PHARMA, INC. (US) | 2020-02-13 | — | — | WO | disclosed |