Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CD74 | P04233 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21684642 | 0.91 | TBXA2R (0.48) | AGTR1AGTR2RAB9APLK1TBXA2R | |
| SCHEMBL21703186 | 0.87 | TBXA2R (0.50) | AGTR1AGTR2RAB9AKCNK13TBXA2R | |
| SCHEMBL21703232 | 0.78 | MAP4K1 (0.49) | BRD4CD74MIFMEN1KMT2A | |
| SCHEMBL21703260 | 0.78 | MAP4K1 (0.49) | AGTR1AGTR2RAB9AHTTL3MBTL1 | |
| SCHEMBL21702962 | 0.77 | MAP4K1 (0.51) | AGTR1AGTR2MEN1KMT2AHTT | |
| SCHEMBL21685620 | 0.77 | ALDH1A1 (0.55) | AGTR1AGTR2RAB9ALMNAHTT | |
| SCHEMBL21703340 | 0.76 | MAP4K1 (0.47) | AGTR1AGTR2RAB9AMEN1KMT2A | |
| SCHEMBL21703262 | 0.75 | MAP4K1 (0.51) | AGTR1AGTR2TBXA2R | |
| SCHEMBL21703266 | 0.75 | MAP4K1 (0.52) | AGTR1AGTR2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21684490 | 0.75 | MAP4K1 (0.48) | RAB9ALMNATSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033784-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | SITARI PHARMA, INC. (US) | 2020-02-13 | — | — | WO | disclosed |