Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21701260 | 1.00 | JAK3 (0.77) | JAK3BTK | |
| SCHEMBL16764802 | 0.87 | JAK3 (1.00) | JAK3 | |
| SCHEMBL16764800 | 0.87 | JAK3 (1.00) | JAK3 | |
| SCHEMBL16765494 | 0.87 | JAK3 (1.00) | JAK3BTK | |
| SCHEMBL21705093 | 0.86 | JAK3 (0.57) | JAK3BTK | |
| SCHEMBL21704936 | 0.86 | BTK (0.65) | JAK3BTK | |
| SCHEMBL21701257 | 0.86 | BTK (0.65) | JAK3BTK | |
| SCHEMBL21678532 | 0.86 | JAK3 (0.84) | JAK3BTK | |
| SCHEMBL21678535 | 0.86 | JAK3 (0.84) | JAK3BTK | |
| SCHEMBL31070078 | 0.86 | JAK3 (0.56) | JAK3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112823005-A | Pyrrolopyrimidine ITK inhibitors | 阿克拉瑞斯治疗股份有限公司 | 2021-05-18 | — | — | CN | disclosed |
| WO-2020033955-A1 | PYRROLOPYRIMIDINE ITK INHIBITORS | ACLARIS THERAPEUTICS, INC. (US) | 2020-02-13 | — | — | WO | disclosed |