Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070078 | 0.92 | JAK3 (0.56) | JAK3BTK | |
| SCHEMBL21701260 | 0.86 | JAK3 (0.77) | JAK3BTK | |
| SCHEMBL21704938 | 0.86 | JAK3 (0.77) | JAK3BTK | |
| SCHEMBL21704936 | 0.83 | BTK (0.65) | JAK3BTK | |
| SCHEMBL21701257 | 0.83 | BTK (0.65) | JAK3BTK | |
| SCHEMBL21705160 | 0.83 | JAK3 (0.58) | JAK3BTK | |
| SCHEMBL21705061 | 0.81 | JAK3 (0.50) | JAK3BTK | |
| SCHEMBL21701320 | 0.81 | JAK3 (0.50) | JAK3BTK | |
| SCHEMBL21678374 | 0.80 | JAK3 (0.77) | JAK3BTK | |
| SCHEMBL21704948 | 0.78 | JAK3 (0.53) | JAK3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033955-A1 | PYRROLOPYRIMIDINE ITK INHIBITORS | ACLARIS THERAPEUTICS, INC. (US) | 2020-02-13 | — | — | WO | disclosed |