Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16765296 | 1.00 | JAK3 (1.00) | JAK3 | |
| SCHEMBL21678697 | 0.97 | JAK3 (0.94) | JAK3 | |
| SCHEMBL21678695 | 0.97 | JAK3 (0.94) | JAK3 | |
| SCHEMBL20125385 | 0.88 | JAK3 (0.78) | JAK3 | |
| SCHEMBL16764962 | 0.88 | JAK3 (1.00) | JAK3 | |
| SCHEMBL16764961 | 0.88 | JAK3 (1.00) | JAK3 | |
| SCHEMBL21678502 | 0.88 | JAK3 (0.78) | JAK3 | |
| SCHEMBL21704984 | 0.88 | JAK3 (0.78) | JAK3 | |
| SCHEMBL16764589 | 0.87 | JAK3 (1.00) | JAK3 | |
| SCHEMBL16765383 | 0.87 | JAK3 (0.80) | JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033955-A1 | PYRROLOPYRIMIDINE ITK INHIBITORS | ACLARIS THERAPEUTICS, INC. (US) | 2020-02-13 | — | — | WO | disclosed |