Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21704952 | 0.88 | JAK3 (1.00) | JAK3 | |
| SCHEMBL16765296 | 0.88 | JAK3 (1.00) | JAK3 | |
| SCHEMBL21678465 | 0.88 | JAK3 (0.75) | JAK3IRAK4 | |
| SCHEMBL21678464 | 0.88 | JAK3 (0.75) | JAK3IRAK4 | |
| SCHEMBL21678695 | 0.85 | JAK3 (0.94) | JAK3 | |
| SCHEMBL21678697 | 0.85 | JAK3 (0.94) | JAK3 | |
| SCHEMBL21701310 | 0.84 | JAK3 (0.67) | JAK3IRAK4 | |
| SCHEMBL21705140 | 0.84 | JAK3 (0.67) | JAK3IRAK4 | |
| SCHEMBL21701281 | 0.83 | JAK3 (0.67) | JAK3 | |
| SCHEMBL19596073 | 0.81 | JAK3 (0.84) | JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318565-A1 | PYRROLO[2,3-D]PYRIMIDINYL, PYRROLO[2,3-B]PYRAZINYL AND PYRROLO[2,3-D]PYRIDINYL ACRYLAMIDES | Pfizer Inc (US) | 2018-05-09 | — | — | EP | disclosed |