Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.83 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21682493 | 0.91 | PDE5A (0.83) | PDE5A | |
| SCHEMBL22028304 | 0.91 | PDE5A (1.00) | PDE5A | |
| SCHEMBL20568425 | 0.91 | PDE5A (1.00) | PDE5A | |
| SCHEMBL21682533 | 0.89 | PDE5A (0.95) | PDE5AHDAC1HDAC2HDAC6 | |
| SCHEMBL20567811 | 0.87 | PDE5A (1.00) | PDE5A | |
| SCHEMBL6501252 | 0.87 | PDE5A (0.80) | PDE5AHDAC1HDAC2HDAC6 | |
| SCHEMBL20568085 | 0.87 | PDE5A (0.92) | PDE5A | |
| SCHEMBL31651389 | 0.87 | PDE5A (0.92) | PDE5A | |
| Citric Acid SCHEMBL21682596 | 0.86 | PDE5A (0.73) | PDE5A | |
| Sulfuric Acid SCHEMBL7012672 | 0.86 | PDE5A (0.78) | PDE5AHDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210322413-A1 | NITRIC OXIDE RELEASING PHOSPHODIESTERASE TYPE 5 INHIBITOR | NICOX S.A. (FR) | 2021-10-21 | — | — | US | disclosed |
| WO-2020030489-A1 | NITRIC OXIDE RELEASING PHOSPHODIESTERASE TYPE 5 INHIBITOR | NICOX S.A. (FR) | 2020-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210322413-A1 | NITRIC OXIDE RELEASING PHOSPHODIESTERASE TYPE 5 INHIBITOR | PDE5A, PDE6A, PDE3A | PDE5A 1/4885HDAC1 1298/4885HDAC2 1346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.