SCHEMBL21705263

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15047632	0.93	KMT2A (0.63)	KMT2AMEN1ATMCYP2D6HRH3
	SCHEMBL16202965	0.87	KMT2A (0.74)	KMT2AMEN1ATMCYP2D6HRH3
	SCHEMBL21705256	0.85	KMT2A (0.76)	KMT2AMEN1ATMCYP2D6HRH3
	SCHEMBL18891134	0.85	MEN1 (0.55)	KMT2AMEN1ATMHRH3HPGD
	SCHEMBL21705258	0.84	NPSR1 (0.52)	KMT2AMEN1ATMHRH3HPGD
	SCHEMBL21705701	0.83	KMT2A (0.56)	KMT2AMEN1ATMCYP2D6HRH3
	SCHEMBL2821475	0.83	ATM (0.77)	KMT2AMEN1ATMHPGDKDM4E
	SCHEMBL21705703	0.82	KMT2A (0.55)	KMT2AMEN1ATMCYP2D6HRH3
	Maleic Acid SCHEMBL27397848	0.80	MEN1 (0.49)	KMT2AMEN1ATMHRH3HPGD
	Maleic Acid SCHEMBL27397850	0.80	MEN1 (0.49)	KMT2AMEN1ATMHRH3HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.