Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 18/20 | 0.48 |
| ▸ | ITGB6 | P18564 | 8/20 | 0.40 |
| ▸ | ITGB5 | P18084 | 6/20 | 0.40 |
| ▸ | ITGB8 | P26012 | 6/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24336636 | 0.88 | ITGAV (0.46) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL21705492 | 0.85 | ITGB3 (0.58) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL26480237 | 0.84 | ITGAV (0.45) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL21705963 | 0.84 | ITGAV (0.44) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL24363125 | 0.81 | ITGAV (0.75) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL22029428 | 0.81 | ITGAV (0.75) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL26480092 | 0.78 | ITGAV (0.48) | ITGAVITGB3ITGB6ITGB1ITGA4 | |
| SCHEMBL21705782 | 0.77 | ITGAV (0.53) | ITGAVITGB3ITGB6ITGB1ITGA4 | |
| SCHEMBL21705426 | 0.77 | ITGAV (0.53) | ITGAVITGB3ITGB6ITGB1ITGA4 | |
| SCHEMBL26480096 | 0.77 | ITGAV (0.48) | ITGAVITGB3ITGB6ITGB5ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033724-A1 | INTEGRIN ANTAGONISTS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-02-13 | — | — | WO | disclosed |