Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.77 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.77 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.58 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036020 | 0.95 | FFAR1 (0.76) | FFAR1FFAR4PARP10 | |
| SCHEMBL434231 | 0.87 | FFAR1 (0.59) | FFAR1FFAR4PARP10 | |
| Benzyloxyphenylpropanoic Acid SCHEMBL1134648 | 0.87 | FFAR1 (1.00) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL1744939 | 0.87 | FFAR1 (1.00) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL5037942 | 0.86 | FFAR1 (0.75) | FFAR1FFAR4PARP10 | |
| Benzyloxyphenylpropanoic Acid SCHEMBL30117578 | 0.85 | FFAR1 (0.97) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL2912575 | 0.84 | FFAR1 (0.66) | FFAR1FFAR4PARP10NR4A2 | |
| SCHEMBL1796796 | 0.84 | FFAR1 (0.77) | FFAR1FFAR4AKR1B1LTA4HEPHX2 | |
| SCHEMBL5033197 | 0.84 | FFAR1 (0.77) | FFAR1FFAR4AKR1B1LTA4HEPHX2 | |
| SCHEMBL1395785 | 0.83 | PARP10 (0.68) | FFAR1FFAR4PARP10NR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115477684-A | Substituted 3-thiazolidine-2,4-diketone Mcl-1 protein inhibitor, preparation method and application | 湖南科技大学 | 2022-12-16 | — | — | CN | claimed |
| CN-115477684-A | Substituted 3-thiazolidine-2,4-diketone Mcl-1 protein inhibitor, preparation method and application | 湖南科技大学 | 2022-12-16 | — | — | CN | disclosed |
| CN-109843866-A | YAP1 inhibitors targeting YAP1 interaction with OCT4 | H·李·莫菲特癌症中心研究有限公司 | 2019-06-04 | — | — | CN | disclosed |
| EP-2349252-A2 | SYNERGISTIC COMBINATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS AND ANTIMICROTUBULE AGENTS | Exelixis, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-2346821-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | Exelixis, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |
| CN-1050376-A | Acyl-CoA: cholesterol acyltransferase inhibitor | WARBER LAMBERT CO (US) | 1991-04-03 | — | — | CN | disclosed |
| EP-0337714-A2 | HIV protease inhibitors useful for the treatment of aids | MERCK & CO. INC. (US) | 1989-10-18 | — | — | EP | disclosed |