Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.76 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.69 |
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170636 | 0.95 | FFAR1 (0.77) | FFAR1FFAR4PARP10 | |
| SCHEMBL2772440 | 0.86 | FFAR1 (1.00) | FFAR1FFAR4 | |
| SCHEMBL434231 | 0.86 | FFAR1 (0.59) | FFAR1FFAR4CES1ALDH1A1MAPT | |
| SCHEMBL2912575 | 0.86 | FFAR1 (0.66) | FFAR1FFAR4PARP10 | |
| SCHEMBL5037942 | 0.84 | FFAR1 (0.75) | FFAR1FFAR4PARP10 | |
| SCHEMBL2173032 | 0.83 | FFAR1 (0.74) | FFAR1FFAR4CES1PARP10 | |
| Benzyloxyphenylpropanoic Acid SCHEMBL1134648 | 0.81 | FFAR1 (1.00) | FFAR1FFAR4 | |
| SCHEMBL1744939 | 0.81 | FFAR1 (1.00) | FFAR1FFAR4 | |
| SCHEMBL1744943 | 0.81 | FFAR1 (1.00) | FFAR1FFAR4 | |
| SCHEMBL1747130 | 0.81 | FFAR1 (1.00) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076784-A2 | NEW INHIBITORS OF CYCLOPHILINS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-06-30 | — | — | WO | disclosed |