Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 3/20 | 0.44 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.44 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.38 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21707441 | 1.00 | SLC6A12 (0.44) | SLC6A12SLC6A11SLC6A13GABRR1GABRR2 | |
| SCHEMBL24631168 | 1.00 | SLC6A12 (0.44) | SLC6A12SLC6A11SLC6A13GABRR1GABRR2 | |
| SCHEMBL23369826 | 1.00 | SLC6A12 (0.44) | SLC6A12SLC6A11SLC6A13GABRR1GABRR2 | |
| SCHEMBL19032979 | 0.76 | SLC6A12 (0.52) | SLC6A12SLC6A11SLC6A13GABRR1GABRR2 | |
| SCHEMBL1401472 | 0.76 | SLC6A12 (0.59) | SLC6A12SLC6A11SLC6A13GABRR1HSD11B1 | |
| SCHEMBL7269130 | 0.71 | MEN1 (0.54) | SLC6A12SLC6A11SLC6A13HSD11B1MEN1 | |
| SCHEMBL20573120 | 0.71 | MEN1 (0.54) | SLC6A12SLC6A11SLC6A13HSD11B1MEN1 | |
| SCHEMBL3915502 | 0.71 | MEN1 (0.54) | SLC6A12SLC6A11SLC6A13HSD11B1MEN1 | |
| SCHEMBL20573107 | 0.71 | MEN1 (0.54) | SLC6A12SLC6A11SLC6A13HSD11B1MEN1 | |
| SCHEMBL5449679 | 0.71 | MEN1 (0.54) | SLC6A12SLC6A11SLC6A13HSD11B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020029762-A1 | PREPARATION METHOD FOR FUSED TRICYCLIC γ-AMINO ACID DERIVATIVE AND INTERMEDIATE THEREOF | 四川海思科制药有限公司 | 2020-02-13 | — | — | WO | disclosed |