Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.71 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.71 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | AKT1 | P31749 | 9/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.38 |
| ▸ | PRKACA | P17612 | 5/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.38 |
| ▸ | PKN2 | Q16513 | 4/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 4/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 4/20 | 0.37 |
| ▸ | CLK2 | P49760 | 3/20 | 0.37 |
| ▸ | PRKX | P51817 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170239 | 1.00 | CHRNB2 (0.71) | CHRNB2CHRNA4HTR2AAKT1CHRNB4 | |
| SCHEMBL2168879 | 1.00 | CHRNB2 (0.71) | CHRNB2CHRNA4HTR2AAKT1CHRNB4 | |
| SCHEMBL2170244 | 1.00 | CHRNB2 (0.71) | CHRNB2CHRNA4HTR2AAKT1CHRNB4 | |
| SCHEMBL2169514 | 1.00 | CHRNB2 (0.71) | CHRNB2CHRNA4HTR2AAKT1CHRNB4 | |
| SCHEMBL621422 | 1.00 | CHRNB2 (0.71) | CHRNB2CHRNA4HTR2AAKT1CHRNB4 | |
| SCHEMBL2168872 | 1.00 | CHRNB2 (0.71) | CHRNB2CHRNA4HTR2AAKT1CHRNB4 | |
| SCHEMBL621421 | 1.00 | CHRNB2 (0.71) | CHRNB2CHRNA4HTR2AAKT1CHRNB4 | |
| SCHEMBL4247313 | 0.87 | CHRNB2 (0.66) | CHRNB2CHRNA4AKT1CHRNB4CHRNA3 | |
| SCHEMBL1691835 | 0.87 | CHRNB2 (0.66) | CHRNB2CHRNA4AKT1CHRNB4CHRNA3 | |
| SCHEMBL14138470 | 0.87 | CHRNB2 (0.72) | CHRNB2CHRNA4AKT1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011144192-A | COMPOUND CAPABLE OF ACTIVATING CHOLINERGIC RECEPTOR | TARGACEPT INC | 2011-07-28 | — | — | JP | disclosed |