Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16236839 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL28522731 | 0.92 | KMT2A (0.35) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL16992971 | 0.90 | POLB (0.37) | KMT2AALDH1A1TSHRGAAPOLB | |
| Hydrochloric Acid SCHEMBL28526027 | 0.90 | KMT2A (0.34) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL16992936 | 0.86 | PDK1 (0.36) | SMN1; SMN2KMT2AALDH1A1TSHRGAA | |
| SCHEMBL16237218 | 0.86 | PDK1 (0.36) | SMN1; SMN2KMT2AALDH1A1TSHRGAA | |
| SCHEMBL18261880 | 0.86 | PDK1 (0.36) | SMN1; SMN2KMT2AALDH1A1TSHRGAA | |
| SCHEMBL16236640 | 0.86 | PDK1 (0.38) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL16992898 | 0.86 | PDK1 (0.38) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL18261877 | 0.86 | PDK1 (0.38) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3121164-B1 | SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2020-02-19 | — | — | EP | disclosed |