Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16257366 | 1.00 | HTR2B (0.43) | HTR2BTHRBTP53POLBLMNA | |
| SCHEMBL17700845 | 0.91 | HTR2B (0.53) | HTR2BTHRBTP53POLBLMNA | |
| SCHEMBL17700935 | 0.89 | MEN1 (0.44) | HTR2BTHRBTP53POLBLMNA | |
| SCHEMBL16237617 | 0.89 | MEN1 (0.44) | HTR2BTHRBTP53POLBLMNA | |
| SCHEMBL17700928 | 0.87 | POLB (0.51) | HTR2BTHRBTP53POLBLMNA | |
| SCHEMBL21707952 | 0.87 | POLB (0.51) | HTR2BTHRBTP53POLBLMNA | |
| SCHEMBL21727545 | 0.83 | HTR2B (0.53) | HTR2BTHRBTP53POLBLMNA | |
| SCHEMBL17700926 | 0.83 | HTR2B (0.53) | HTR2BTHRBTP53POLBLMNA | |
| SCHEMBL18407892 | 0.83 | THRB (0.41) | THRBTP53POLBLMNATDP1 | |
| SCHEMBL16236804 | 0.82 | TP53 (0.46) | THRBTP53POLBLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3121164-B1 | SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2020-02-19 | — | — | EP | disclosed |