Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.42 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.42 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.42 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15550319 | 0.88 | ALOX15 (0.57) | KMT2AKDM4EMEN1RECQLSMN1; SMN2 | |
| SCHEMBL1994828 | 0.86 | KMT2A (0.54) | KMT2AKDM4EMEN1RECQLSMN1; SMN2 | |
| SCHEMBL29009914 | 0.84 | KMT2A (0.51) | KMT2AKDM4EMEN1RECQLSMN1; SMN2 | |
| SCHEMBL15558476 | 0.83 | ALOX15 (0.63) | KMT2AKDM4EMEN1RECQLHTR7 | |
| SCHEMBL1997560 | 0.83 | KMT2A (0.54) | KMT2AKDM4EMEN1RECQLSMN1; SMN2 | |
| SCHEMBL15558002 | 0.82 | ALOX15 (0.62) | KMT2AKDM4EMEN1RECQLSMN1; SMN2 | |
| SCHEMBL15558761 | 0.82 | ALOX15 (0.62) | KMT2AKDM4EMEN1RECQLSMN1; SMN2 | |
| SCHEMBL499472 | 0.81 | KMT2A (0.67) | KMT2AKDM4EMEN1RECQLSMN1; SMN2 | |
| SCHEMBL249930 | 0.81 | TYR (0.54) | ACHE | |
| SCHEMBL27739467 | 0.81 | KMT2A (0.51) | KMT2AKDM4EMEN1RECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609870-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |