Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.62 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.48 |
| ▸ | FPR2 | P25090 | 5/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MAT2A | P31153 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15665092 | 0.92 | CNR2 (0.49) | FFAR1SCN9AFPR2BACE1MAT2A | |
| SCHEMBL13284534 | 0.92 | CNR2 (0.49) | FFAR1SCN9AFPR2BACE1MAT2A | |
| SCHEMBL2172455 | 0.86 | SCN9A (0.60) | FFAR1SCN9AFPR2F10 | |
| Hydrochloric Acid SCHEMBL2169819 | 0.85 | SCN9A (0.59) | FFAR1SCN9AFPR2F10 | |
| SCHEMBL3061734 | 0.82 | F10 (0.58) | FFAR1F10BACE1CYP2C9CYP2C19 | |
| SCHEMBL15665295 | 0.82 | F10 (0.58) | FFAR1F10BACE1CYP2C9CYP2C19 | |
| SCHEMBL9104214 | 0.78 | FFAR1 (0.53) | FFAR1BACE1CNR2CYP2C8CYP2C9 | |
| SCHEMBL1274844 | 0.78 | FFAR1 (0.53) | FFAR1BACE1CNR2CYP2C8CYP2C9 | |
| SCHEMBL13723813 | 0.78 | SYK (0.46) | F10MAT2A | |
| SCHEMBL17294200 | 0.78 | SYK (0.46) | F10MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346821-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | Exelixis, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |