Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | BCR | P11274 | 2/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.41 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19008144 | 0.85 | MAP4K4 (0.49) | MAP4K4LTA4HCCR5GRM2HDAC1 | |
| SCHEMBL21709587 | 0.84 | ALDH1A1 (0.44) | TACR1CYP2D6CYP3A4MEN1MAPK1 | |
| SCHEMBL22243488 | 0.84 | ABL1 (0.43) | ABL1BCRDDR1DDR2MAP4K4 | |
| SCHEMBL9609586 | 0.84 | ABL1 (0.43) | ABL1BCRDDR1DDR2MAP4K4 | |
| SCHEMBL14315491 | 0.84 | ABL1 (0.43) | ABL1BCRDDR1DDR2MAP4K4 | |
| SCHEMBL9610931 | 0.84 | ABL1 (0.43) | ABL1BCRDDR1DDR2MAP4K4 | |
| SCHEMBL24566587 | 0.82 | MAP4K4 (0.45) | ABL1BCRDDR1DDR2MAP4K4 | |
| SCHEMBL24192361 | 0.82 | MAP4K4 (0.45) | ABL1BCRDDR1DDR2MAP4K4 | |
| SCHEMBL24192780 | 0.82 | MAP4K4 (0.45) | ABL1BCRDDR1DDR2MAP4K4 | |
| SCHEMBL24192805 | 0.81 | ABL1 (0.43) | ABL1BCRDDR1DDR2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200048288-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048288-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | MAP3K6, PIK3CA, MAP3K20 | ABL1 16/4885BCR 621/4885DDR1 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.