SCHEMBL21709685

SCHEMBL21709685

Cc1ccc(C2(c3ccc(C)cc3)c3cc(-c4ccc(/C=C5\C(=O)c6ccccc6C5=C(C#N)C#N)s4)ccc3-c3sc4c(c32)C(c2ccc(C)cc2)(c2ccc(C)cc2)c2cc(-c3ccc(/C=C5\C(=O)c6ccccc6C5=C(C#N)C#N)s3)ccc2-4)cc1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
HPGD P15428 1/20 0.35
RECQL P46063 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PRF1 P14222 11/20 0.33
APP P05067 1/20 0.32
SNCA P37840 1/20 0.32
EGFR P00533 1/20 0.32
RET P07949 1/20 0.32
KDR P35968 1/20 0.32
CTRC Q99895 1/20 0.32
MEN1 O00255 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21706385 0.95 PRF1 (0.34) KMT2AALDH1A1MAPTTHRBHPGD
SCHEMBL20043835 0.92 PRF1 (0.30) PRF1
SCHEMBL20044325 0.91 MGAT2 (0.32) ALDH1A1MAPTHPGDNPSR1PRF1
SCHEMBL22382821 0.87
SCHEMBL24637687 0.86 EGFR (0.39) KMT2AALDH1A1MAPTTHRBHPGD
SCHEMBL21156739 0.84 ALDH1A1 (0.32) KMT2AALDH1A1MAPTTHRBHPGD
SCHEMBL20247155 0.84 MGAT2 (0.30)
SCHEMBL21156751 0.84 ALDH1A1 (0.31) KMT2AALDH1A1MAPTTHRBHPGD
SCHEMBL24637699 0.84 ALDH1A1 (0.32) KMT2AALDH1A1MAPTTHRBHPGD
SCHEMBL24637688 0.83 PRF1 (0.31) KMT2AALDH1A1MAPTTHRBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11183637-B2 Organic photodetector Raynergy Tek Incorporation (TW) 2021-11-23 US disclosed
US-20200052216-A1 ORGANIC PHOTODETECTOR MERCK PATENT GMBH (DE) 2020-02-13 US disclosed