Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA6 | P23280 | 4/20 | 0.46 |
| ▸ | CA7 | P43166 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.46 |
| ▸ | CA5A | P35218 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21173521 | 1.00 | SIGMAR1 (0.57) | SIGMAR1CA12CA6CA7CA9 | |
| SCHEMBL20017646 | 1.00 | SIGMAR1 (0.57) | SIGMAR1CA12CA6CA7CA9 | |
| SCHEMBL18430248 | 1.00 | SIGMAR1 (0.57) | SIGMAR1CA12CA6CA7CA9 | |
| SCHEMBL18531458 | 1.00 | SIGMAR1 (0.57) | SIGMAR1CA12CA6CA7CA9 | |
| SCHEMBL18430891 | 1.00 | SIGMAR1 (0.57) | SIGMAR1CA12CA6CA7CA9 | |
| SCHEMBL23131807 | 0.98 | SIGMAR1 (0.59) | SIGMAR1CA12CA6CA7CA9 | |
| SCHEMBL21173520 | 0.98 | SIGMAR1 (0.59) | SIGMAR1CA12CA6CA7CA9 | |
| SCHEMBL18531456 | 0.98 | SIGMAR1 (0.59) | SIGMAR1CA12CA6CA7CA9 | |
| SCHEMBL18823178 | 0.98 | SIGMAR1 (0.59) | SIGMAR1CA12CA6CA7CA9 | |
| SCHEMBL5057409 | 0.98 | SIGMAR1 (0.59) | SIGMAR1CA12CA6CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740475-B1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | CRINETICS PHARMACEUTICALS INC (US) | 2022-04-20 | — | — | EP | disclosed |
| WO-2021039800-A1 | METHOD FOR PREPARING ENANTIOMER OF SULFOXIDE COMPOUND, AND SYSTEM FOR PREPARING ENANTIOMER | 学校法人東京理科大学 | 2021-03-04 | — | — | WO | disclosed |
| US-10889561-B2 | Process of making somatostatin modulators | Crinetics Pharmaceuticals, Inc. (US) | 2021-01-12 | — | — | US | disclosed |
| US-20200048219-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | Crinetics Pharmaceuticals, Inc. | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048219-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | SSTR5, SSTR4, SSTR2 | SIGMAR1 827/4885CA12 930/4885CA6 940/4885 |
| US-10889561-B2 | Process of making somatostatin modulators | SSTR5, SSTR4, SSTR2 | SIGMAR1 827/4885CA12 930/4885CA6 940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.