⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1895739 | 0.78 | — | — | |
| SCHEMBL17652504 | 0.78 | — | — | |
| SCHEMBL373913 | 0.78 | — | — | |
| Cyclohexane SCHEMBL28020421 | 0.75 | — | — | |
| SCHEMBL3985587 | 0.74 | — | — | |
| SCHEMBL2859317 | 0.69 | — | — | |
| SCHEMBL700606 | 0.69 | — | — | |
| SCHEMBL1561090 | 0.68 | — | — | |
| SCHEMBL13980972 | 0.65 | — | — | |
| SCHEMBL20484201 | 0.65 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033709-A1 | INHIBITING DEUBIQUITINASE USP25 AND USP28 | FORMA THERAPEUTICS, INC. (US) | 2020-02-13 | — | — | WO | disclosed |