Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15748734 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ANPC1MAPTHSD17B10 | |
| SCHEMBL18653596 | 0.85 | PTPN1 (0.42) | SMN1; SMN2RAB9ANPC1MAPTPTPN1 | |
| SCHEMBL18382545 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1MAPTHSD17B10 | |
| SCHEMBL24224793 | 0.84 | HIF1A (0.41) | MAPTPTPN1CA1CA2KDM4E | |
| SCHEMBL16369588 | 0.84 | TP53 (0.47) | SMN1; SMN2RAB9ANPC1MAPTPTPN1 | |
| SCHEMBL30434097 | 0.81 | PTPN1 (0.39) | SMN1; SMN2RAB9ANPC1MAPTPTPN1 | |
| SCHEMBL25220396 | 0.81 | PTPN1 (0.39) | SMN1; SMN2RAB9ANPC1MAPTPTPN1 | |
| SCHEMBL8148873 | 0.77 | P4HTM (0.59) | PTPN1CA1CA2 | |
| SCHEMBL15747956 | 0.77 | RAB9A (0.53) | SMN1; SMN2RAB9ANPC1MAPTPTPN1 | |
| SCHEMBL13978263 | 0.76 | RAB9A (0.52) | SMN1; SMN2RAB9ANPC1MAPTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11370899-B2 | Rubber composition for tires, and pneumatic tires | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2022-06-28 | — | — | US | disclosed |
| US-20200048437-A1 | RUBBER COMPOSITION FOR TIRES, AND PNEUMATIC TIRES | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2020-02-13 | — | — | US | disclosed |