Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 13/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21712097 | 0.90 | TSHR (0.52) | WDR5MEN1KMT2AHPGDTSHR | |
| SCHEMBL21712106 | 0.87 | WDR5 (0.51) | WDR5MEN1KMT2AMMP13HPGD | |
| SCHEMBL21712098 | 0.82 | WDR5 (0.49) | WDR5SMN1; SMN2 | |
| SCHEMBL21712099 | 0.82 | WDR5 (0.49) | WDR5SMN1; SMN2 | |
| SCHEMBL21712079 | 0.80 | WDR5 (0.43) | WDR5MEN1KMT2AMMP13HPGD | |
| SCHEMBL21712086 | 0.80 | HPGD (0.43) | WDR5MEN1KMT2AMMP13HPGD | |
| SCHEMBL21711932 | 0.79 | WDR5 (0.45) | WDR5MEN1KMT2AMMP13HPGD | |
| SCHEMBL21711562 | 0.79 | WDR5 (0.49) | WDR5MEN1KMT2AMMP13 | |
| SCHEMBL21817242 | 0.79 | TSHR (0.54) | WDR5MEN1KMT2AHPGDTSHR | |
| SCHEMBL21711806 | 0.78 | WDR5 (0.44) | WDR5MEN1KMT2AMMP13HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10807959-B2 | WDR5-MLL1 inhibitors and modulators | VANDERBILT UNIVERSITY (US) | 2020-10-20 | — | — | US | disclosed |
| US-20200055824-A1 | WDR5-MLL1 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10807959-B2 | WDR5-MLL1 inhibitors and modulators | WDR5, WDR1, WDR3 | WDR5 1/4885MEN1 468/4885KMT2A 48/4885 |
| US-20200055824-A1 | WDR5-MLL1 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | WDR5 1/4885MEN1 468/4885KMT2A 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.