Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5909305 | 0.81 | ALDH1A1 (0.50) | ATMALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL14731464 | 0.81 | RECQL (0.50) | ALDH1A1KMT2AMEN1ADRA1ARECQL | |
| SCHEMBL14730753 | 0.81 | RECQL (0.50) | ALDH1A1KMT2AMEN1ADRA1ARECQL | |
| SCHEMBL10330247 | 0.77 | HPGD (0.56) | ATMALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL2219100 | 0.76 | SMN1; SMN2 (0.60) | ALDH1A1MAPTMYCGRM5HPGD | |
| SCHEMBL25972070 | 0.76 | ALDH1A1 (0.49) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL5908996 | 0.76 | ALDH1A1 (0.64) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL12442637 | 0.76 | HPGD (0.62) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL29944223 | 0.76 | HPGD (0.62) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL14290099 | 0.75 | RECQL (0.43) | ALDH1A1MAPTRECQLGRM5APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020029980-A1 | SMAD3 INHIBITORS | MOEXA PHARMACEUTICALS LIMITED (CN) | 2020-02-13 | — | — | WO | disclosed |