SCHEMBL2171289

SCHEMBL2171289

O=C(CF)CC(=O)C(F)F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.34
HPGD P15428 1/20 0.32
CASP1 P29466 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11517688 0.78 CES2 (0.42) CES2HPGD
SCHEMBL11518372 0.76 TDP1 (0.45) CES2HPGD
SCHEMBL27466399 0.76
SCHEMBL620772 0.76
SCHEMBL9971728 0.75
SCHEMBL11517280 0.74 CES2 (0.32) CES2HPGD
Acetone SCHEMBL28144848 0.74 CES2 (0.37) CES2
SCHEMBL7252681 0.74 CES2 (0.42) CES2
Water SCHEMBL542921 0.73
SCHEMBL18319325 0.72 CES2 (0.45) CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5141549-A Method of fabricating rare earth doped planar optical waveguide for integrated optical circuit THE CHARLES STARK DRAPER LABORATORIES (US) 1992-08-25 US claimed
US-5039753-A Polymers comprising betadiketone groups and polymerizable compositions containing said polymers LOCTITE (IRELAND) LTD (IE) 1991-08-13 US claimed
EP-0313387-A2 Polymers comprising betadiketone groups and polymerizable compositions containing said polymers LOCTITE (IRELAND) Ltd. (IE) 1989-04-26 EP claimed
WO-2023144793-A1 POL THETA INHIBITORS RHIZEN PHARMACEUTICALS AG (CH) 2023-08-03 WO disclosed
US-10695723-B2 Dye sensitized photoactive surfaces MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-06-30 US disclosed
US-9891526-B2 Pattern forming method JSR CORPORATION (JP) 2018-02-13 US disclosed
US-20160367946-A1 DYE SENSITIZED PHOTOACTIVE SURFACES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-12-22 US disclosed
US-9487868-B2 Pattern-forming method JSR CORPORATION (JP) 2016-11-08 US disclosed
US-20160131978-A1 PATTERN FORMING METHOD JSR CORPORATION (JP) 2016-05-12 US disclosed
US-20150191829-A1 PATTERN-FORMING METHOD JSR CORPORATION (JP) 2015-07-09 US disclosed
US-8927201-B2 Multilayer resist process pattern-forming method and multilayer resist process inorganic film-forming composition JSR CORPORATION (JP) 2015-01-06 US disclosed
US-5792779-A CARDIOVASCULAR DISORDERS; ANGINA MERCK & CO., INC. (US) 1998-08-11 US disclosed
WO-1997030708-A1 PYRIDINONE THROMBIN INHIBITORS MERCK & CO., INC. (US) 1997-08-28 WO disclosed
EP-0394126-B1 Compounds and complexes especially useful in medical imaging MEDGENIX DIAGNOSTIC (BE) 1994-07-20 EP disclosed
US-5141549-A Method of fabricating rare earth doped planar optical waveguide for integrated optical circuit THE CHARLES STARK DRAPER LABORATORIES (US) 1992-08-25 US disclosed
US-5039753-A Polymers comprising betadiketone groups and polymerizable compositions containing said polymers LOCTITE (IRELAND) LTD (IE) 1991-08-13 US disclosed
US-5039753-A Polymers comprising betadiketone groups and polymerizable compositions containing said polymers LOCTITE (IRELAND) LTD (IE) 1991-08-13 US disclosed
EP-0394126-A1 Compounds and complexes especially useful in medical imaging MEDGENIX DIAGNOSTICS (BE) 1990-10-24 EP disclosed
EP-0313387-A2 Polymers comprising betadiketone groups and polymerizable compositions containing said polymers LOCTITE (IRELAND) Ltd. (IE) 1989-04-26 EP disclosed
US-4501602-A FORMING OF OXIDE SOOT FROM BETA-DIKETONATE METAL COMPLEXES CORNING GLASS WORKS (US) 1985-02-26 US disclosed