SCHEMBL217137

SCHEMBL217137

[NH]C(=O)C1CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216549 0.97 CES2 (0.58)
SCHEMBL218386 0.97 CES2 (0.58)
SCHEMBL26180 0.97
SCHEMBL217427 0.97 CES2 (0.58)
SCHEMBL217105 0.97 CES2 (0.58)
SCHEMBL215921 0.97 CES2 (0.58)
SCHEMBL8517604 0.97 CES2 (0.58)
SCHEMBL216556 0.93
Sulfur Dioxide SCHEMBL461977 0.89 CES2 (0.50)
SCHEMBL5660 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1030 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4247797-A1 2-PHENYLBENZOTRIAZOL-5-AMINE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS (HBV) INFECTION F. Hoffmann-La Roche AG (CH) 2023-09-27 EP claimed
CN-116768949-A Compound with anticancer effect based on chemical modification of 3' -deoxyadenosine 南京工业大学 2023-09-19 CN claimed
US-20230286927-A1 2-PHENYLBENZOTRIAZOL-5-AMINE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS (HBV) INFECTION HOFFMANN-LA ROCHE INC. (US) 2023-09-14 US claimed
CN-116438176-A 2-phenylbenzotriazol-5-amine derivatives for the treatment and prevention of Hepatitis B Virus (HBV) infection 豪夫迈·罗氏有限公司 2023-07-14 CN claimed
CN-115181148-A Compound with anti-tumor effect based on cordycepin through derivatization 南京工业大学 2022-10-14 CN claimed
CN-114728009-A Preventing or treating diseases and disorders associated with tissue damage 李晓祥 2022-07-08 CN claimed
WO-2022106588-A1 2-PHENYLBENZOTRIAZOL-5-AMINE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS (HBV) INFECTION F. HOFFMANN-LA ROCHE AG (CH) 2022-05-27 WO claimed
CN-113966325-A Fluorine-containing substituted imidazole salt compound, preparation method thereof, medicinal composition and application thereof 厦门华绰生物医药科技有限公司 2022-01-21 CN claimed
EP-3458455-B1 NOVEL PYRAZINE COMPOUNDS WITH OXYGEN, SULFUR AND NITROGEN LINKER FOR THE TREATMENT OF INFECTIOUS DISEASES HOFFMANN LA ROCHE (CH) 2021-06-16 EP claimed
CN-109153682-B Novel pyrazine compounds with oxygen, sulfur and nitrogen linkers for the treatment of infectious diseases 豪夫迈·罗氏有限公司 2021-05-25 CN claimed
US-5516907-A ANTIINFLAMMATORY AGENTS G.D. SEARLE & CO. (US) 1996-05-14 US claimed
US-5510496-A ANTIINFLAMMATORY AGENTS G.D. SEARLE & CO. (US) 1996-04-23 US claimed
US-5508426-A ANTIARTHRITIC AGENT G. D. SEARLE & CO. (US) 1996-04-16 US claimed
US-5466823-A Antiinflammatory agents; FDA Orange book listed patent for Celebrex G.D. SEARLE & CO. (US) 1995-11-14 US claimed
EP-0542867-A4 METHODS OF PREVENTING OR DECREASING TISSUE DAMAGE BY NOVEL ANTIOXIDANTS AND FREE RADICAL SCAVENGERS 1993-07-28 EP claimed
EP-0542867-A1 METHODS OF PREVENTING OR DECREASING TISSUE DAMAGE BY NOVEL ANTIOXIDANTS AND FREE RADICAL SCAVENGERS GENSIA, INC. (US) 1993-05-26 EP claimed
EP-0495091-A4 AICA RIBOSIDE ANALOGS 1993-01-07 EP claimed
EP-0495091-A1 AICA RIBOSIDE ANALOGS GENSIA, INC. (US) 1992-07-22 EP claimed
WO-1992002213-A1 METHODS OF PREVENTING OR DECREASING TISSUE DAMAGE BY NOVEL ANTIOXIDANTS AND FREE RADICAL SCAVENGERS GENSIA PHARMACEUTICALS, INC. (US) 1992-02-20 WO claimed
WO-1992002214-A1 AICA RIBOSIDE ANALOGS GENSIA PHARMACEUTICALS, INC. (US) 1992-02-20 WO claimed