Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19464246 | 0.80 | ALOX5 (0.43) | ALOX5MEN1KMT2AMGLLATM | |
| SCHEMBL2299566 | 0.79 | SCN9A (0.53) | ALOX5 | |
| SCHEMBL2378804 | 0.77 | ALOX5 (0.43) | ALOX5MEN1KMT2AMGLLATM | |
| SCHEMBL21683097 | 0.77 | ALOX5 (0.43) | ALOX5MEN1KMT2AMGLLATM | |
| SCHEMBL5230422 | 0.75 | HSD17B10 (0.43) | ALOX5MEN1KMT2AMGLLATM | |
| SCHEMBL3121487 | 0.74 | USP30 (0.47) | ALOX5ATML3MBTL1 | |
| SCHEMBL31127631 | 0.74 | CHRNB4 (0.45) | ALOX5MEN1KMT2AMGLL | |
| SCHEMBL12372623 | 0.72 | ALOX5 (0.40) | ALOX5MEN1KMT2AMGLLATM | |
| SCHEMBL22055528 | 0.72 | ALOX5 (0.54) | ALOX5MEN1KMT2AMGLLALDH1A1 | |
| SCHEMBL19690169 | 0.72 | ALOX5 (0.54) | ALOX5MEN1KMT2AMGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033382-A1 | COMPOUNDS USEFUL IN MODULATING THE FARNESOID X RECEPTOR AND METHODS OF MAKING AND USING THE SAME | INORBIT THERAPEUTICS AB (SE) | 2020-02-13 | — | — | WO | disclosed |