⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL31307175 | 0.76 | — | — | |
| SCHEMBL30210798 | 0.66 | DRD2 (0.31) | — | |
| SCHEMBL22412870 | 0.65 | — | — | |
| SCHEMBL2171110 | 0.65 | — | — | |
| SCHEMBL3572585 | 0.64 | — | — | |
| SCHEMBL2172092 | 0.64 | — | — | |
| SCHEMBL16510902 | 0.62 | — | — | |
| SCHEMBL16008544 | 0.62 | — | — | |
| SCHEMBL6059492 | 0.62 | — | — | |
| SCHEMBL30210650 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220062296-A1 | COMBINATIONS OF GABAA ALPHA 5 AGONISTS AND SV2A INHIBITORS AND METHODS OF USING IN THE TREATMENT OF COGNITIVE IMPAIRMENT | AGENEBIO, INC. | 2022-03-03 | — | — | US | disclosed |
| EP-2346335-B1 | PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2018-11-14 | — | — | EP | disclosed |
| US-8853125-B2 | Pyrazole compounds for controlling invertebrate pests | BASF SE (DE) | 2014-10-07 | — | — | US | disclosed |
| EP-2312947-B1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2014-01-01 | — | — | EP | disclosed |
| EP-2346335-A2 | PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2011-07-27 | — | — | EP | disclosed |
| US-20110173726-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2011-07-14 | — | — | US | disclosed |
| WO-2010034738-A2 | PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2010-04-01 | — | — | WO | disclosed |