Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172544 | 0.78 | MEN1 (0.51) | GAAMAPK1ALDH1A1HPGDNLRP1 | |
| SCHEMBL16179563 | 0.72 | KMT2A (0.47) | GAAALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL12336850 | 0.72 | HSP90AB1 (0.34) | — | |
| SCHEMBL1286610 | 0.69 | GAA (0.44) | GAAMAPK1ALDH1A1NPSR1HPGD | |
| SCHEMBL1281996 | 0.69 | MAPT (0.51) | MAPK1ALDH1A1HPGDNLRP1MAPT | |
| SCHEMBL1281680 | 0.69 | GAA (0.44) | GAAMAPK1ALDH1A1NPSR1HPGD | |
| SCHEMBL1282491 | 0.68 | GAA (0.45) | GAAMAPK1ALDH1A1NPSR1HPGD | |
| SCHEMBL19086744 | 0.67 | KMT2A (0.51) | GAAALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL19280768 | 0.67 | KMT2A (0.51) | GAAALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL19733283 | 0.67 | KMT2A (0.51) | GAAALDH1A1NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190122-A1 | Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them | BASF SE (DE) | 2011-08-04 | — | — | US | disclosed |
| EP-2346839-A1 | TRIAZOLE AND IMIDAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING THEM | BASF SE (DE) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010040717-A1 | TRIAZOLE AND IMIDAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING THEM | BASF SE (DE) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190122-A1 | Triazole and Imidazole Compounds, Use Thereof and Agents Containing Them | ABAT, OAT, TYR | GAA 503/4885MAPK1 1624/4885ALDH1A1 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.