Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008986 | 0.83 | SMN1; SMN2 (0.37) | HRH3KCNH2CYP2D6 | |
| SCHEMBL18375130 | 0.83 | SMN1; SMN2 (0.37) | HRH3KCNH2CYP2D6 | |
| SCHEMBL15196701 | 0.82 | ALDH1A1 (0.42) | HRH3KCNH2CYP2D6ALDH1A1 | |
| SCHEMBL20009059 | 0.80 | GRM5 (0.35) | HRH3KCNH2CYP2D6MAPT | |
| SCHEMBL7851975 | 0.80 | HRH3 (0.41) | HRH3MAPT | |
| SCHEMBL26203667 | 0.80 | ALDH1A1 (0.32) | HRH3KCNH2CYP2D6ALDH1A1 | |
| SCHEMBL20009056 | 0.79 | HRH3 (0.37) | HRH3KCNH2CYP2D6 | |
| SCHEMBL20682344 | 0.79 | TSHR (0.38) | KCNH2MAPT | |
| SCHEMBL26203664 | 0.79 | DPP4 (0.37) | ALDH1A1 | |
| SCHEMBL20314925 | 0.77 | JAK3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3836917-A1 | NOVEL SULFONAMIDEUREA COMPOUNDS | Inflazome Limited (IE) | 2021-06-23 | — | — | EP | disclosed |
| WO-2020035464-A1 | NOVEL SULFONAMIDEUREA COMPOUNDS | INFLAZOME LIMITED (IE) | 2020-02-20 | — | — | WO | disclosed |