SCHEMBL2172332

SCHEMBL2172332

Cc1cc(OCc2ccccc2)c([C@]2(O)O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1C1OCCO1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TACR2 P21452 3/20 0.33
PTPN1 P18031 8/20 0.33
PTPN2 P17706 3/20 0.33
PTPN11 Q06124 3/20 0.33
CDC25B P30305 6/20 0.32
NT5E P21589 1/20 0.31
HTR1A P08908 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
PTPN6 P29350 2/20 0.31
GJB2 P29033 1/20 0.30
SSTR1 P30872 1/20 0.30
SSTR2 P30874 1/20 0.30
SSTR4 P31391 1/20 0.30
SSTR3 P32745 1/20 0.30
SSTR5 P35346 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2172327 1.00 TACR2 (0.33) TACR2PTPN1PTPN2PTPN11CDC25B
SCHEMBL2174063 0.83 TACR2 (0.36) TACR2PTPN1PTPN2PTPN11CDC25B
SCHEMBL2174055 0.83 TACR2 (0.36) TACR2PTPN1PTPN2PTPN11CDC25B
SCHEMBL21553819 0.83
SCHEMBL590553 0.82 TACR2 (0.31) TACR2BCHEACHE
SCHEMBL13425524 0.82 TACR2 (0.31) TACR2BCHEACHE
SCHEMBL590554 0.82 TACR2 (0.31) TACR2BCHEACHE
SCHEMBL2960359 0.82 TACR2 (0.37) TACR2PTPN1PTPN2PTPN11CDC25B
SCHEMBL2960356 0.82 TACR2 (0.37) TACR2PTPN1PTPN2PTPN11CDC25B
SCHEMBL20140033 0.81 TACR2 (0.34) TACR2PTPN1PTPN2PTPN11CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2076503-B1 C-PHENYL GLYCITOL COMPOUND FOR THE TREATMENT OF DIABETES TAISHO PHARMACEUTICAL CO LTD (JP) 2013-07-17 EP disclosed
US-7973012-B2 C-phenyl glycitol compound TAISHO PHARMACEUTICAL CO., LTD (JP) 2011-07-05 US disclosed
US-20100022460-A1 C-PHENYL GLYCITOL COMPOUND TAISHO PHARMACEUTICAL CO., LTD. (JP) 2010-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022460-A1 C-PHENYL GLYCITOL COMPOUND SLC5A1, SLC5A2, SLC2A1 TACR2 957/4885PTPN1 1941/4885PTPN2 2384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.