SCHEMBL2174063

SCHEMBL2174063

Cc1cc(OCc2ccccc2)c([C@]2(O)O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1C=O

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TACR2 P21452 3/20 0.36
ERN1 O75460 2/20 0.36
PTPN1 P18031 8/20 0.34
CDC25B P30305 6/20 0.34
NT5E P21589 1/20 0.34
PTPN2 P17706 3/20 0.34
PTPN11 Q06124 3/20 0.34
PTPN6 P29350 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
HTR1A P08908 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2174055 1.00 TACR2 (0.36) TACR2ERN1PTPN1CDC25BNT5E
SCHEMBL20741919 0.92 ERN1 (0.35) TACR2ERN1PTPN1CDC25BNT5E
SCHEMBL20139433 0.90 TACR2 (0.37) TACR2ERN1PTPN1CDC25BNT5E
SCHEMBL2960359 0.84 TACR2 (0.37) TACR2PTPN1CDC25BNT5EPTPN2
SCHEMBL2960356 0.84 TACR2 (0.37) TACR2PTPN1CDC25BNT5EPTPN2
SCHEMBL2172332 0.83 TACR2 (0.33) TACR2PTPN1CDC25BNT5EPTPN2
SCHEMBL2172327 0.83 TACR2 (0.33) TACR2PTPN1CDC25BNT5EPTPN2
SCHEMBL20139455 0.82 TACR2 (0.36) TACR2ERN1PTPN1CDC25BNT5E
SCHEMBL20140011 0.81 NT5E (0.35) TACR2PTPN1CDC25BNT5EPTPN2
SCHEMBL589372 0.80 ERN1 (0.36) TACR2ERN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2076503-B1 C-PHENYL GLYCITOL COMPOUND FOR THE TREATMENT OF DIABETES TAISHO PHARMACEUTICAL CO LTD (JP) 2013-07-17 EP disclosed
US-7973012-B2 C-phenyl glycitol compound TAISHO PHARMACEUTICAL CO., LTD (JP) 2011-07-05 US disclosed
US-20100022460-A1 C-PHENYL GLYCITOL COMPOUND TAISHO PHARMACEUTICAL CO., LTD. (JP) 2010-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022460-A1 C-PHENYL GLYCITOL COMPOUND SLC5A1, SLC5A2, SLC2A1 TACR2 957/4885ERN1 1890/4885PTPN1 1941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.