SCHEMBL21724070

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21724292	0.88	MAPK1 (0.53)	MAP3K5MAPK1NPC1RAB9AALDH1A1
	SCHEMBL21724104	0.85	MAPT (0.52)	MAPK1NPC1RAB9AALDH1A1SMN1; SMN2
	SCHEMBL21724017	0.83	NPC1 (0.62)	MAP3K5MAPK1NPC1RAB9AALDH1A1
	SCHEMBL12606911	0.82	NPC1 (0.46)	MAP3K5MAPK1NPC1RAB9AALDH1A1
	Hydrochloric Acid SCHEMBL1780811	0.81	NPC1 (0.46)	MAP3K5MAPK1NPC1RAB9AALDH1A1
	SCHEMBL21724024	0.78	MAP3K5 (0.36)	MAP3K5MAPK1SMN1; SMN2
	SCHEMBL29841360	0.77	MAP3K5 (0.48)	MAP3K5MAPK1TP53TUBB4ATUBB
	SCHEMBL28866960	0.77	MAP3K5 (0.48)	MAP3K5MAPK1TP53TUBB4ATUBB
	SCHEMBL16917368	0.74	MAPK1 (0.46)	MAPK1NPC1RAB9AALDH1A1TP53
	SCHEMBL16568930	0.74	ADORA3 (0.44)	MAPK1NPC1RAB9AALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.