Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19036257 | 0.81 | GAA (0.70) | GAALMNAHSD17B10ALDH1A1 | |
| SCHEMBL28023339 | 0.79 | GAA (0.54) | GAALMNAHSD17B10ALDH1A1 | |
| SCHEMBL6321209 | 0.77 | GAA (0.52) | GAALMNAHSD17B10ALDH1A1 | |
| SCHEMBL6314494 | 0.77 | GAA (0.52) | GAALMNAHSD17B10ALDH1A1 | |
| SCHEMBL6314268 | 0.77 | GAA (0.52) | GAALMNAHSD17B10ALDH1A1 | |
| SCHEMBL7262827 | 0.76 | — | — | |
| SCHEMBL17652003 | 0.76 | — | — | |
| SCHEMBL17652006 | 0.74 | ALOX15 (0.39) | LMNAHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL2171395 | 0.74 | ALOX15 (0.39) | LMNAHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL15256397 | 0.73 | GAA (0.39) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583285-A | N- (imidazo [1,2-b ] pyridazin-3-yl) -1-cyclohexyl-2H-indazole-5-carboxamide and N- (pyrazolo [1,5-a ] pyrimidin-3-yl) -1-cyclohexyl-2H-indazole-5-carboxamide derivatives as IRAK4 inhibitors for the treatment of asthma | 阿斯利康(瑞典)有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-102209706-B | Process for producing N, N-dialkyl lactamide | PURAC BIOCHEM BV | 2014-07-23 | — | — | CN | disclosed |
| CN-102209706-A | Process for producing N, N-dialkyl lactamide | JAN KRIEKEN VAN | 2011-10-05 | — | — | CN | disclosed |
| EP-2346812-A1 | PROCESS FOR MANUFACTURING N,N-DIALKYL LACTAMIDE | PURAC Biochem BV (NL) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010037776-A1 | PROCESS FOR MANUFACTURING N,N-DIALKYL LACTAMIDE | PURAC BIOCHEM BV (NL) | 2010-04-08 | — | — | WO | disclosed |