Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724639 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9ALTA4HF2 | |
| SCHEMBL21724436 | 0.84 | HDAC8 (0.47) | CA1CA2HDAC8 | |
| SCHEMBL21724435 | 0.84 | HDAC8 (0.47) | CA1CA2HDAC8 | |
| SCHEMBL21724635 | 0.82 | SPHK1 (0.45) | — | |
| SCHEMBL21724637 | 0.82 | SPHK1 (0.45) | — | |
| SCHEMBL21724621 | 0.82 | SPHK1 (0.45) | — | |
| SCHEMBL21724618 | 0.82 | SPHK1 (0.45) | — | |
| Hydrochloric Acid SCHEMBL21724243 | 0.80 | LTA4H (0.51) | SMN1; SMN2NPC1RAB9ALTA4H | |
| Hydrochloric Acid SCHEMBL21724241 | 0.80 | LTA4H (0.51) | SMN1; SMN2NPC1RAB9ALTA4H | |
| SCHEMBL16685886 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3836971-A1 | CONJUGATES AND METHODS OF USING THE SAME | Flagship Pioneering Innovations V, Inc. (US) | 2021-06-23 | — | — | EP | disclosed |
| WO-2020037009-A1 | CONJUGATES AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2020-02-20 | — | — | WO | disclosed |