Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 3/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140328 | 0.97 | NCF1 (0.52) | NCF1NOS2BACE1CA12CA9 | |
| SCHEMBL84064 | 0.97 | NCF1 (0.52) | NCF1NOS2BACE1CA12CA9 | |
| SCHEMBL29376435 | 0.97 | NCF1 (0.52) | NCF1NOS2BACE1CA12CA9 | |
| SCHEMBL11208328 | 0.95 | NCF1 (0.50) | NCF1NOS2BACE1CA12CA9 | |
| SCHEMBL21545979 | 0.95 | NCF1 (0.50) | NCF1NOS2BACE1CA12CA9 | |
| SCHEMBL23198380 | 0.95 | NCF1 (0.50) | NCF1NOS2BACE1CA12CA9 | |
| SCHEMBL598283 | 0.95 | NCF1 (0.50) | NCF1NOS2BACE1CA12CA9 | |
| Potassium SCHEMBL5616117 | 0.95 | NCF1 (0.50) | NCF1NOS2BACE1CA12CA9 | |
| SCHEMBL5616115 | 0.95 | NCF1 (0.50) | NCF1NOS2BACE1CA12CA9 | |
| SCHEMBL8622817 | 0.95 | NCF1 (0.50) | NCF1NOS2BACE1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111875555-B | Synthesis method of saccharin-6-acetate | 南京合创药业有限公司 | 2022-07-19 | — | — | CN | claimed |
| CN-111875555-A | Synthesis method of saccharin-6-acetate | 南京合创药业有限公司 | 2020-11-03 | — | — | CN | claimed |
| CN-117986271-A | Cell cycle regulator, and pharmaceutical preparation and application thereof | 贵州大学 | 2024-05-07 | — | — | CN | disclosed |
| CN-117069656-A | Preparation method of deuterated alcohol | 氘益有氘(天津)药业有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-111875555-B | Synthesis method of saccharin-6-acetate | 南京合创药业有限公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-111875555-A | Synthesis method of saccharin-6-acetate | 南京合创药业有限公司 | 2020-11-03 | — | — | CN | disclosed |
| WO-2020037109-A1 | PROCESSES FOR FLUORINATION | DOW AGROSCIENCES LLC (US) | 2020-02-20 | — | — | WO | disclosed |
| CN-109863136-A | For finding the chemical proteomics method of the covalent ligands of protein target | 南加利福尼亚大学 | 2019-06-07 | — | — | CN | disclosed |
| CN-105486791-A | Fe3O4@SiO2@G magnetic adsorbent and method for detecting 16 anti-staling agents in vegetable by using same | INSPECTION AND QUARANTINE TECH CENTER OF CHONGQING ENTRY EXIT INSPECTION AND QUARANTINE BUREAU | 2016-04-13 | — | — | CN | disclosed |
| CN-1050190-A | The preparation method of novel sulfoamido thiophene | CHEM PHARM FORSCH GMBH (AT) | 1991-03-27 | — | — | CN | disclosed |