Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | GABRP | O00591 | 2/20 | 0.67 |
| ▸ | GABRD | O14764 | 2/20 | 0.67 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.67 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.67 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.67 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.67 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.67 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.67 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.67 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.67 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.67 |
| ▸ | GABRE | P78334 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29424976 | 1.00 | MAPT (0.71) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL29817732 | 0.91 | MAPT (0.76) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL29817749 | 0.89 | MAPT (0.73) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL27940928 | 0.89 | MAPT (0.73) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL21724929 | 0.89 | MAPT (0.73) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL21731007 | 0.87 | KDM4E (0.59) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL28429347 | 0.87 | STAT3 (0.52) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL29817702 | 0.86 | MAPT (0.70) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL21724817 | 0.84 | KMT2A (0.52) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL29424954 | 0.84 | KMT2A (0.52) | MAPTKDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396291-A | Application of 1-amide and 1-hydrazide substituted beta-carboline derivative as agricultural bactericide | 南京农业大学 | 2023-07-07 | — | — | CN | disclosed |
| WO-2020037116-A1 | SMALL MOLECULE PYRIN-DOMAIN TARGETED NLRP3 INFLAMMASOME INHIBITORS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2020-02-20 | — | — | WO | disclosed |
| WO-2020037116-A1 | SMALL MOLECULE PYRIN-DOMAIN TARGETED NLRP3 INFLAMMASOME INHIBITORS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2020-02-20 | — | — | WO | disclosed |