Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21725377 | 0.89 | MEN1 (0.43) | ENPP3ENPP1ADORA2AMCL1ACMSD | |
| SCHEMBL21725421 | 0.88 | PIM1 (0.45) | ENPP3ENPP1MCL1ACMSDKDM4E | |
| SCHEMBL17969975 | 0.85 | ENPP3 (0.53) | ENPP3ENPP1ADORA2AMCL1ACMSD | |
| SCHEMBL19397409 | 0.84 | ENPP3 (0.51) | ENPP3ENPP1ADORA2AMCL1ACMSD | |
| SCHEMBL19650630 | 0.84 | MEN1 (0.45) | ENPP3ENPP1ADORA2AMCL1ACMSD | |
| SCHEMBL19650575 | 0.84 | ENPP1 (0.42) | ENPP3ENPP1ADORA2AMCL1ACMSD | |
| SCHEMBL19650656 | 0.83 | CYP1A1 (0.47) | ADORA2AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL19009501 | 0.82 | ENPP1 (0.55) | ENPP3ENPP1MCL1ACMSDKDM4E | |
| SCHEMBL19650544 | 0.81 | MEN1 (0.40) | ENPP3ENPP1ADORA2AMCL1ACMSD | |
| SCHEMBL19397514 | 0.81 | MCL1 (0.46) | ENPP3ENPP1ADORA2AMCL1ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10566543-B2 | Pyrimidine derivative and organic electroluminescent devices | HODOGAYA CHEMICAL CO., LTD. (JP) | 2020-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10566543-B2 | Pyrimidine derivative and organic electroluminescent devices | TYMS, TYMP, DPYD | ENPP3 69/4885ENPP1 73/4885ADORA2A 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.